NUGLY IM/166R

NUGLY IM/166R – Food Grade Chitosan Oligosaccharide Powder (Sea Source)

Low-Molecular-Weight Marine Chitosan Oligosaccharide for Food and Formulation Development

Sea Source
  • Derived from marine chitosan (sea source)

  • Food grade bioactive, ≥90% purity

  • Enhances skin hydration and moisture retention

  • Repairs and strengthens the skin barrier

  • Provides anti-aging benefits (smooths wrinkles, improves elasticity)

  • Exhibits antioxidant and antimicrobial activity

  • Water-soluble and easy to incorporate into formulations

  • Ideal for lotions, serums, masks, and creams

Synonyms: Chitosan Oligosaccharide (COS), Marine Chitosan Oligosaccharide, Sea-Source COS, Oligochitosan, Chitooligosaccharide, Low-Molecular-Weight Marine Chitosan
Degree of deacetylation
Not separately stated as a minimum
Molecular weight
Not separately stated as a range
Appearance
Yellow powder
Impurities
Inclusion-free
Sulphated ash
≤1.0%

Properties

PropertyValueTest methodNote
Degree of deacetylationNot separately stated as a minimum91.52%
Molecular weightNot separately stated as a range782.6 Da
AppearanceYellow powderPass
ImpuritiesInclusion-freePass
Sulphated ash≤1.0%0.72%
Moisture≤10.0%3.46%
Arsenic salts≤0.5 mg/kgPass
Mould count≤200 CFU/gPass

Packaging & Quality

ItemDetail
Available package sizes25 g sample pack, 1 kg pack and commercial bulk packaging by quotation
Food-grade clarificationThe product is marketed as Food Grade. The attached COA does not independently state FDA approval, GRAS status or compliance with a named food-regulatory standard. Confirm market-specific regulatory eligibility before use.

Tiered Pricing

QuantityPrice / quotePackagingShipping
25 g sample$40 totalSample packFree shipping
1 kg$119/kg1 kg pack50% U.S. tariff plus $60 FedEx shipping
2–99 kgRequest QuoteCommercial bulk packagingFreight and applicable charges quoted separately
100–499 kgRequest QuoteCommercial bulk packagingFreight and applicable charges quoted separately
500 kg or moreRequest QuoteIndustrial bulk packagingFreight, documentation and delivery terms quoted separately

Product Overview

Food Grade Chitosan Oligosaccharide Powder Supplier for Commercial Formulation Development

Food Grade Chitosan Oligosaccharide Powder is gaining attention among food developers, beverage formulators, nutraceutical manufacturers and ingredient-sourcing teams because it offers a different formulation profile from conventional high-molecular-weight chitosan.

NUGLY IM/166R is a marine-source chitosan oligosaccharide developed for commercial formulation evaluation. Its shortened polymer chains can provide easier aqueous processing and lower viscosity than longer-chain native chitosan, making it relevant when manufacturers need a chitosan-based ingredient that can be evaluated in modern food and wellness product systems.

Selecting the right chitosan oligosaccharide, however, requires more than choosing a product labeled “food grade.” Formulators must consider molecular structure, source, compatibility, processing conditions, documentation and regulatory requirements together.

What Is Food Grade Chitosan Oligosaccharide Powder?

Chitosan oligosaccharide, frequently abbreviated as COS, is produced by reducing longer chitosan polymers into shorter molecular chains. This change in chain length affects how the material disperses, dissolves and interacts with other ingredients.

Native chitosan is generally associated with longer polymer chains, higher solution viscosity and greater dependence on acidic processing. COS is processed into smaller fractions that may be easier to incorporate into compatible water-based systems.

For commercial manufacturers, this distinction can affect:

  • Ingredient preparation time
  • Solution viscosity
  • Mixing and dispersion
  • Compatibility with liquid-processing systems
  • Interaction with other charged ingredients
  • Stability during product development
  • Manufacturing scalability

These potential advantages do not mean that COS will perform identically in every formulation. Product developers should evaluate the material inside the complete finished-product matrix rather than relying on performance observed in water alone.

Why Molecular Size Matters in Formulation

Molecular size is one of the most important factors affecting chitosan behavior. When chitosan chains are shortened, the material’s viscosity and aqueous-processing characteristics can change considerably.

A lower-molecular-weight material may be useful when a manufacturer wants to evaluate chitosan without creating the thick solution commonly associated with larger chitosan polymers. This can be relevant in formulations where texture, clarity, flow behavior or rapid mixing must be carefully controlled.

However, lower molecular weight is not automatically better for every product. Higher-molecular-weight chitosan may be preferred when film formation, coating strength, encapsulation or structural performance is more important than low viscosity.

The correct choice depends on the finished product and the function the formulator expects the ingredient to perform.

Understanding Marine-Source Chitosan Oligosaccharide

Marine chitosan is generally produced from chitin obtained from sea-source raw materials. This differentiates it from mushroom-derived and insect-derived chitosan, although all three belong to the broader chitosan family.

Source affects more than marketing language. It may influence:

  • Supplier qualification requirements
  • Allergen review
  • Raw-material traceability
  • Labeling decisions
  • Customer acceptance
  • Regional regulatory documentation
  • Brand positioning

Marine origin should not be used as a substitute for analytical specifications. Two marine-source COS products can behave differently if their molecular weight, degree of deacetylation, purity profile or production process differs.

Manufacturers should also review allergen and cross-contact documentation before using a marine-source ingredient in food, supplement or personal-care products. A food-grade description does not remove the need for a product-specific allergen assessment.

Water Compatibility Does Not Guarantee Finished-Product Compatibility

Water solubility or dispersibility can simplify early-stage formulation, but performance in purified water is only the starting point.

A commercial formulation may contain proteins, minerals, acids, sweeteners, flavor compounds, gums, stabilizers, preservatives and other charged ingredients. Each component can influence how chitosan oligosaccharide behaves.

Important variables include:

  • Final formulation pH
  • Ingredient concentration
  • Water hardness
  • Mixing speed and duration
  • Processing temperature
  • Order of ingredient addition
  • Ionic strength
  • Protein and polysaccharide content
  • Storage conditions
  • Packaging environment

A successful bench test should reproduce the intended manufacturing conditions as closely as possible. Testing only in purified water may fail to reveal interactions that appear later in the complete formulation.

Charge Behavior and Ingredient Interaction

Chitosan contains amino groups that can develop positive charge under suitable conditions. This cationic behavior is one reason chitosan and its oligosaccharides are studied across food, beverage and material-formulation systems.

Charge can influence interactions with negatively charged components such as certain proteins, pectins, suspended particles and other polymers. Depending on the formulation, these interactions may be useful—or they may create haze, precipitation, aggregation or unwanted changes in texture.

Formulators should therefore evaluate:

  • Whether the product contains negatively charged ingredients
  • Whether the operating pH supports the intended interaction
  • Whether aggregation occurs during mixing
  • Whether sediment develops during storage
  • Whether the material changes clarity, flavor or mouthfeel
  • Whether processing conditions remain consistent during scale-up

In beverage development, charge interactions can also influence clarification and suspended-particle behavior. The technical guide on chitosan for beverage clarification explains why dosage, pH and mixing conditions must be optimized rather than assumed.

Evaluating COS in Food and Beverage Systems

Commercial food and beverage development requires more than confirming that an ingredient can be mixed into a laboratory sample. The finished system must remain acceptable throughout manufacturing, packaging, transportation and its intended shelf life.

A useful evaluation process may include:

  1. Preparing a defined stock solution or dispersion
  2. Recording the water quality, pH and temperature
  3. Adding the material under controlled mixing conditions
  4. Monitoring clarity, texture and sediment formation
  5. Testing compatibility with flavors, proteins and stabilizers
  6. Conducting heat and cold-cycle evaluations
  7. Monitoring performance during storage
  8. Repeating the test at pilot scale
  9. Comparing multiple production batches where possible

Manufacturers exploring COS for beverage processing should avoid assuming that a material suitable for one beverage will automatically work in another. Fruit beverages, protein drinks, fermented products and powdered drink mixes can have very different pH, charge and stability requirements.

Nutraceutical Formulation Considerations

Nutraceutical manufacturers may evaluate chitosan oligosaccharide in capsules, sachets, powder systems or other delivery formats. Suitability depends on more than the ingredient’s general identity.

Development teams should determine:

  • Whether the material is compatible with other active ingredients
  • Whether it absorbs moisture inside a powder blend
  • Whether it changes flow or filling behavior
  • Whether it interacts with minerals or charged compounds
  • Whether the intended serving level is technically and legally appropriate
  • Whether the finished product remains stable over time
  • Whether the supplier documentation supports the target market

General research associated with chitosan oligosaccharides should not automatically be converted into claims for a finished supplement. Clinical, biological or digestive-health statements require evidence appropriate to the specific ingredient, formulation and target market.

For a broader look at formulation categories and sourcing considerations, review the guide to digestive health ingredients.

Food Grade Is a Qualification Process, Not Just a Label

The phrase “food grade” should represent a documented suitability assessment rather than a marketing description alone.

Before approving a COS ingredient, quality and procurement teams should review the documents required for their specific market. Depending on the application and country, this may include:

  • Current batch documentation
  • Safety documentation
  • Allergen and cross-contact declarations
  • Country-of-origin information
  • Manufacturing-process information
  • Contaminant and microbiological limits
  • Traceability records
  • Regulatory statements
  • Shelf-life or retest information
  • Change-control procedures

The documentation required for a conventional food ingredient may differ from what is needed for a dietary supplement, beverage-processing aid or cosmetic formulation. Buyers should define their documentation requirements before commercial purchasing.

The food grade chitosan supplier guide provides additional context for evaluating suppliers and documentation across food-processing systems.

Avoiding Unsupported Product Claims

Chitosan oligosaccharide is discussed in scientific literature across multiple research areas. However, a study involving one type of COS does not automatically establish the same performance for every commercial grade.

Research outcomes may change according to:

  • Molecular-weight distribution
  • Degree of deacetylation
  • Biological source
  • Purification process
  • Concentration
  • Experimental conditions
  • Formulation ingredients
  • Test model
  • Duration of exposure

Commercial content should clearly separate general COS research from properties verified for a specific product or production batch.

Terms such as “antioxidant,” “antimicrobial,” “digestive support,” “skin repair” and “anti-aging” should not be presented as guaranteed product benefits unless supported by appropriate product-specific evidence and legally compliant claim substantiation.

Likewise, “clean label,” “natural” and “premium” are not universal regulatory classifications. Their acceptability can depend on local rules, retailer standards and the complete finished-product composition.

From Laboratory Trial to Commercial Production

Moving from a laboratory sample to commercial manufacturing can introduce new variables. Mixing energy, equipment geometry, water volume, processing time and ingredient-addition sequence may differ significantly at production scale.

A controlled development pathway should include:

  1. Define the required function of the ingredient.
  2. Review the supplier’s technical and quality documentation.
  3. Test the material in the complete formulation.
  4. Record concentration, pH, temperature and mixing procedure.
  5. Evaluate compatibility and physical stability.
  6. Conduct pilot-scale production.
  7. Confirm that processing remains consistent at larger volume.
  8. Review the intended product claims and regulatory pathway.
  9. Approve the production batch through the buyer’s quality system.
  10. Maintain traceability from incoming material to finished product.

This process helps prevent a common development mistake: selecting an ingredient because its general category appears suitable without confirming how the actual material behaves inside the finished product.

Choosing a Food Grade Chitosan Oligosaccharide Supplier

A reliable supplier should provide more than a product name and a price. Commercial buyers need accurate communication, current documentation and enough technical information to make a responsible purchasing decision.

When evaluating a Food Grade Chitosan Oligosaccharide Powder supplier, consider:

  • Whether product identity is consistent across documents
  • Whether batch numbers and dates match
  • Whether analytical methods are available when required
  • Whether the supplier can provide allergen information
  • Whether documentation is current
  • Whether specifications remain consistent between batches
  • Whether the supplier communicates manufacturing or specification changes
  • Whether commercial quantities can be supplied consistently
  • Whether technical questions receive clear, evidence-based answers

Supplier selection should support both formulation performance and long-term quality management. A lower purchase price may not provide meaningful savings if inconsistent material causes production delays, failed stability tests or reformulation work.

Why Work With Chitosan Global?

Chitosan Global supplies chitosan materials to manufacturers, formulators, research teams, ingredient importers and commercial product developers. The goal is to help buyers compare materials according to source, molecular characteristics, documentation and intended use rather than relying on broad marketing language.

For NUGLY IM/166R, buyers should complete their own formulation, allergen, regulatory and quality review before commercial approval. This ensures that the selected material aligns with the finished product, manufacturing process and intended market.

To discuss supplier documentation, formulation requirements or commercial purchasing, contact Chitosan Global.

Applications

Beverage Formulation Trials

The product page lists water solubility, making the grade relevant for preliminary beverage and powder-drink evaluations. Test clarity, flavor, pH stability, sedimentation and compatibility in the intended formula.

Learn more

Nutraceutical Product Development

May be evaluated in capsules, sachets, powder blends and other nutraceutical formats, subject to formulation testing and regulatory review for the intended market.

Learn more

Commercial and Private-Label Development

Relevant to ingredient importers, contract manufacturers, private-label companies and product-development teams seeking a marine-source COS ingredient with batch documentation.

Learn more

Directions for Use

For formulation and manufacturing use. Add gradually to the selected formulation phase while mixing. Evaluate dispersion or dissolution at the intended concentration, pH and temperature. Conduct compatibility, stability and application-specific testing before commercial scale-up. No universal use level is established by the COA.

Storage and Handling

Store in a cool, dry and well-ventilated location in the original tightly closed, moisture-resistant container. Protect from direct sunlight, excessive heat, humidity and contamination. Minimize dust generation during handling. Because this is a marine-source material, review the supplier’s allergen and cross-contact documentation before food, supplement or cosmetic use.

Safety Information

Precautionary Statements
Avoid breathing airborne powder. Avoid contact with eyes. Use suitable protective eyewear, gloves and dust-control measures during bulk handling. Wash hands after handling. Follow the current SDS and applicable workplace procedures.

Documentation

PDF

Certificate of Analysis (COA)

Download PDF
Batch / Lot
RX25066S

Certificate of Analysis for NUGLY IM/166R Chitosan Oligosaccharide, Batch RX25066S. The marine-source batch was manufactured on June 11, 2025, with a guarantee period ending June 10, 2027. Analytical results include 91.52% degree of deacetylation, molecular weight of 782.6 Da, 90.33% content, 3.46% moisture and 0.72% sulphated ash. Appearance and impurity requirements passed. Arsenic, lead, total plate count, mould count and Salmonella results passed their stated specifications.

PDF

Material Safety Data Sheet / Safety Data Sheet

Document pending. Please contact us if you need this document before ordering.

Protocols and Articles

Peer-Reviewed Papers

Chitosan: An Overview of Its Properties and Applications

Aranaz I, et al. Polymers. 2021;13(19):3256. This peer-reviewed review discusses how molecular weight, degree of deacetylation, source and chemical structure affect chitosan solubility and application behavior. The research provides category-level context and does not validate this specific commercial batch.

Chitosan-Based Drug Delivery Systems

Bernkop-Schnürch A, Dünnhaupt S. European Journal of Pharmaceutics and Biopharmaceutics. 2012;81(3):463–469. The review examines the cationic and formulation-related properties of chitosan in delivery-system research. It should not be interpreted as evidence that NUGLY IM/166R is approved for pharmaceutical use.

Frequently Asked Questions

What is NUGLY IM/166R chitosan oligosaccharide?

NUGLY IM/166R is a low-molecular-weight, marine-source chitosan oligosaccharide marketed as a Food Grade ingredient for food, beverage, nutraceutical and formulation-development projects.

What is the molecular weight of NUGLY IM/166R?

The current batch COA reports a molecular weight of 782.6 Da. Buyers should confirm the current batch documentation before placing a production order.

Is sea-source chitosan oligosaccharide vegan?

No. A marine-source chitosan oligosaccharide should not be marketed as vegan. Buyers should also request an allergen statement before using it in products intended for allergen-sensitive consumers.

Can this COS be used in functional foods and beverages?

It is marketed as Food Grade and may be evaluated for food and beverage formulations. Buyers must independently confirm applicable food regulations, permitted use levels, labeling and supporting documentation for the target market.

What is the difference between marine COS and mushroom COS?

The principal difference is the biological source of the chitin. Marine COS originates from sea-source material, while mushroom COS originates from fungal biomass. Performance also depends on molecular weight, deacetylation, purity and formulation conditions.