Formulation & Use Cases
At Chitosan Global, we recognize that the real value of an ingredient lies not only in its scientific promise but also in its practical use in formulations. The 3–5 kDa chito-oligosaccharide (COS) offers cosmetic developers a versatile, water-soluble, and biocompatible active that can be integrated into a wide range of products.
Why COS is Easy to Formulate
Water Solubility: Unlike native chitosan, which is often limited by solubility, COS in the 3–5 kDa range disperses easily in aqueous systems.
Mild Profile: Biocompatible and non-phototoxic, making it suitable for sensitive-skin formulations.
Flexible pH Range: Works best around pH 5.0–6.0, aligning with natural skin pH.
Compatible Product Types
COS can be included in most water-based or emulsified cosmetic systems. Common examples include:
Serums & Essences – lightweight formats where COS can act as a collagen-supporting active.
Toners & Mists – fast-absorbing liquids where solubility is key.
Sheet Masks – COS distributes evenly, delivering concentrated skin-conditioning effects.
Gel Creams & Lotions – compatible with humectants (glycerin, hyaluronic acid) and barrier agents (panthenol, ceramides).
After-Sun or Photo-Stress Care – supportive formulations designed to comfort skin exposed to UV.
Suggested Inclusion Levels
Screening range: 0.05–1.0% w/w.
Actual levels should be optimized during formulation trials for stability, efficacy, and sensory feel.
Formulation Tips
COS is cationic, so check compatibility with strongly anionic thickeners or polymers.
Pairs well with UV filters — not as a sunscreen, but as a collagen-care support ingredient alongside approved sun protection systems.
Can be combined with antioxidants (vitamin C, E, plant extracts) to broaden protective effects.
Cosmetic Concept Claims (Safe Wording)
When presenting COS in a cosmetic context, we recommend using compliant, consumer-friendly language such as:
“Supports collagen care for photo-exposed skin.”
“Helps reduce visible effects of photo-stress.”
“Skin-comfort active with in-vitro evidence on fibroblasts.”
Our Role at Chitosan Global
We provide not only high-quality COS ingredients, but also formulation insights that help our partners bring science-backed products to market. Whether your brand focuses on anti-aging serums, recovery creams, or protective skincare lines, COS can serve as a reliable active that aligns with consumer demand for safe, natural, and effective solutions.
Compliance Note
This content is intended for cosmetic research and development professionals. It is not intended as medical advice or as a claim to treat, cure, or prevent any disease.