Carboxymethyl Chitosan

Carboxymethyl Chitosan is a versatile polymer with various applications, primarily in the pharmaceutical field. Its main applications include:

1. Drug Delivery: Carboxymethyl Chitosan is used as a carrier for drug delivery due to its ability to form complexes with drugs and enhance their absorption.

2. Mucoadhesive Properties: Carboxymethyl’s positive charge and solubility over a wide pH range make it an effective mucoadhesive agent, allowing it to stick to mucous membranes and enhance drug absorption.

3. Permeation Enhancement: Carboxymethyl can increase the permeability of drugs across biological membranes, making it a useful excipient in pharmaceutical formulations.

4. DNA Delivery: Carboxymethyl has been explored as a carrier for DNA delivery, taking advantage of its ability to form complexes with DNA and facilitate its uptake by cells.

5. Antimicrobial Properties: Carboxymethyl and its derivatives have shown antimicrobial activity, making them potential candidates for use in antimicrobial applications.

6. Nanoparticle Formation: Carboxymethyl can be used to form nanoparticles, which can be employed in various biomedical applications, including drug delivery and imaging.

7. Oral Delivery: Carboxymethyl-coated nano-complexes have been shown to enhance the oral bioavailability and chemotherapeutic effects of certain drugs.

Degree of Deacetylation - Grade

The degree of deacetylation (DDA) is a crucial factor that determines the properties of chitosan. It refers to the percentage of acetyl groups removed from the chitin structure. Chitosan with a higher degree of deacetylation is more soluble in acidic solutions and has enhanced bioactivity. A higher DDA means that the chitosan will have better performance in applications requiring solubility and bioactivity, making it suitable for a wide range of industrial, cosmetic, and agricultural uses.

Molecular Weight

Molecular weight is a significant property of chitosan that influences its viscosity, solubility, and biological activity. It is usually measured in kilodaltons (kDa) and can vary widely depending on the source and preparation method of the chitosan. Higher molecular weight chitosan tends to have higher viscosity and may form gels, while lower molecular weight chitosan is more soluble and easier to process. Understanding the molecular weight of chitosan is essential for tailoring it to specific applications, such as drug delivery, food preservation, and water treatment.

Certificate of Analysis (CoA)

The Certificate of Analysis (CoA) provides detailed information about the specific batch of chitosan, including its purity, degree of deacetylation, molecular weight, and any contaminants. This document ensures that the product meets the required specifications and standards. It is essential for verifying the quality and consistency of chitosan used in various applications. For example, here is a link to the CoA for -

Pricing

Sample – 1 gram – Free + $10 S&H. Buy Now
Sample 100 Grams
Sea source chitosan
1. 1-25 Kg ($188)
2. 100 kg ($178)
Fungal source chitosan
3. 1-25 kg ($273)
4. 100kg ($254)
Container – Ton Weight

Carboxymethyl Chitosan